The Big 12 is ready to open conference play in its 25th season. All 10 teams are set to play in league games Saturday.
TCU and Baylor will be playing their season openers after being unable to play their scheduled non-conference games because of COVID-19.
Among the games, Kansas State is at No. 3 Oklahoma. The Sooners last season had their five-year road winning streak ended in a 48-41 loss at K-State.
Dave Aranda will make his head coaching debut at Baylor against Kansas and his former boss Les Miles. TCU tries for its 19th consecutive home-opening win against Iowa State.